(DOWNLOAD) "Mechanism of Functional Expression of the Molecular Machines" by Masahiro Kinoshita # Book PDF Kindle ePub Free

eBook details
- Title: Mechanism of Functional Expression of the Molecular Machines
- Author : Masahiro Kinoshita
- Release Date : January 14, 2016
- Genre: Chemistry,Books,Science & Nature,Physics,Life Sciences,
- Pages : * pages
- Size : 1869 KB
Description
This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system.